| Drug Surveillance: The Boston Collaborative Drug Surveillance program reported a study of 9,900 patients with 83,200 drug exposures and found 3,600 adverse drug reactions, 234 (6.5%) of which were attributable to drug interactions. In a study where the medical charts of 1,800 surgical patients were reviewed, researchers found at least one potential drug interaction in 17% of patients. Other studies determined that 19% of nursing home patients received combinations of drugs with known harmful interactions, and adverse drug reactions on medicine wards in hospitals resulted from drug interactions in 22% of patients. In a study of clinic outpatients, a slightly higher ADR percentage of 23% was reported. Clearly, drug interactions present a health risk to patients and a medical challenge for pharmacists and physicians. |