| Digoxin drug drug interactions: Digoxin is used for two indications: the treatment of atrial fibrillation and, less commonly, for congestive heart failure. Drug interactions with digoxin are important because there is a relatively narrow gap between blood concentrations of digoxin that are effective and those that are toxic (ie, it has a narrow therapeutic range). Therefore, a small change in serum levels may lead to inadequate digitalisation or to toxicity. When monitoring for the effects of drug interactions, it is possible to check blood levels of digoxin; however, it is also possible to monitor patients clinically. For example, inadequate digitalisation may result in the reappearance of symptoms of atrial fibrillation such as tachycardia, palpitations and dyspnoea. Toxic levels of digoxin may produce loss of appetite, nausea and vomiting, drowsiness, bradycardia and visual disturbances. Pharmacodynamic interactions "digoxin" Pharmacokinetic interactions "digoxin" Interactions affecting excretion Digoxin herbs interactions |
Drug Interactions
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